PLEOPHARMA, INC. PARTICIPATES IN THE LIFE SCIENCES PA’S LIFE SCIENCE FUTURE CONFERENCE

b83b3ef8737509d112e004b64cdd5bce 2 PLEOPHARMA, INC. PARTICIPATES IN THE LIFE SCIENCES PA'S LIFE SCIENCE FUTURE CONFERENCE

PHOENIXVILLE, Pa., Sept. 19, 2024 /PRNewswire/ — PleoPharma, Inc., a privately held company focused on cannabis related health issues, announced today that their CEO, Ginger Constantine, MD, presented at the Life Sciences PA’s Life Sciences Future Conference.

Dr. Constantine presented data from PleoPharma’s Phase 1 and Phase 2b studies of PP-01, their lead drug candidate intended for the mitigation of Cannabis Withdrawal Syndrome.

About cannabis withdrawal/cannabis use disorder

The US Government reported that in 2023 (samhsa.gov), ~19.2 million Americans had Cannabis Use Disorder with 1.64 million people receiving treatment (~500k inpatient, ~1.1 million outpatient). The number of individuals who have received treatment for cannabis related health problems has grown by an average of 28% annually from 2018 to 2023. People with regular and dependent cannabis use commonly experience significant withdrawal symptoms. There are currently no FDA approved medications for the treatment of cannabis withdrawal syndrome or cannabis use disorder.

About PP-01

PP-01 has a dual mechanism of action targeting suppressed CB1 receptors and neurotransmitter dysregulation in the mesolimbic reward pathway. PP-01 is an investigational product entering Phase 3 that is in development for the mitigation of symptoms related to cannabis withdrawal. PP-01 is intended to be a once daily oral product taken before bedtime providing rapid and sustained efficacy with an excellent safety and tolerability profile.

About PleoPharma, Inc.

PleoPharma, Inc. is a clinical stage development company in the neuropsych and addiction space with a lead asset that is being developed as the first FDA approved treatment for mitigation of Cannabis Withdrawal Syndrome in people with Cannabis Use Disorder.

The PleoPharma team includes a world class management team and board of directors who have produced multiple high value exits, >50 worldwide product approvals, and 100+ INDs.

For more information on PleoPharma, please visit www.PleoPharma.com or email Dawn Halkuff, head of Investor Relations at [email protected].

This release includes ‘forward-looking statements’ regarding the operations of PleoPharma, Inc., actual results may differ from its expectations, estimates, and projections and, consequently, you should not rely on these forward-looking statements as predictions of future events. All statements other than statements of historical facts contained herein are forward-looking statements that reflect the current beliefs and expectations of management of PleoPharma. These forward-looking statements involve significant risks and uncertainties that could cause the actual results to differ materially from those discussed in the forward-looking statements. PleoPharma does not undertake or accept any obligation or undertaking to release any updates or revisions to any forward-looking statements to reflect any change in its expectations or any change in events, conditions or circumstances on which any such statement is based.

CONTACT: [email protected]

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SOURCE PleoPharma, Inc

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